⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407937 | 0.75 | — | — | |
| SCHEMBL4444799 | 0.71 | — | — | |
| SCHEMBL2215844 | 0.71 | — | — | |
| SCHEMBL4063762 | 0.71 | HMGCR (0.31) | — | |
| SCHEMBL4436457 | 0.71 | HMGCR (0.31) | — | |
| SCHEMBL18042534 | 0.70 | PPM1D (0.33) | — | |
| SCHEMBL18042506 | 0.70 | PPM1D (0.33) | — | |
| SCHEMBL1795645 | 0.70 | PPM1D (0.33) | — | |
| SCHEMBL2944859 | 0.69 | PPM1D (0.33) | — | |
| SCHEMBL4333519 | 0.69 | PPM1D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1978020-A1 | Processes for the preparation of statins, particularly rosuvastatin, and intermediates for the preparation thereof | LEK Pharmaceuticals D.D. (SI) | 2008-10-08 | — | — | EP | disclosed |