Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 13/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5120037 | 0.99 | CCR3 (0.56) | CCR3HTR2ATMEM97SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4768602 | 0.87 | CCR3 (0.61) | CCR3HTR2ATMEM97SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4773765 | 0.87 | CCR3 (0.64) | CCR3HTR2ATMEM97 | |
| Hydrochloric Acid SCHEMBL4768538 | 0.87 | CCR3 (0.59) | CCR3HTR2ATMEM97 | |
| SCHEMBL4777172 | 0.87 | CCR3 (0.59) | CCR3HTR2ATMEM97 | |
| Hydrochloric Acid SCHEMBL4778068 | 0.86 | CCR3 (0.58) | CCR3HTR2ATMEM97SLC6A2CCR5 | |
| Hydrochloric Acid SCHEMBL3035491 | 0.85 | CCR3 (0.62) | CCR3HTR2ATMEM97SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4773725 | 0.84 | CCR3 (0.60) | CCR3HTR2ATMEM97SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4773982 | 0.84 | CCR3 (0.62) | CCR3HTR2ATMEM97 | |
| Hydrochloric Acid SCHEMBL4777904 | 0.82 | CCR3 (0.59) | CCR3HTR2ATMEM97SLC6A2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886994-A1 | Cyclic amine compounds as CCR5 antagonists | Takeda Pharmaceutical Company Limited (JP) | 2008-02-13 | — | — | EP | disclosed |