Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777121 | 1.00 | ATM (0.35) | ATMSERPINE1EDNRAMEN1KMT2A | |
| SCHEMBL28117203 | 0.86 | ATM (0.30) | ATM | |
| SCHEMBL28047809 | 0.82 | EPHX1 (0.40) | — | |
| SCHEMBL28449928 | 0.80 | ATM (0.30) | ATM | |
| SCHEMBL10750894 | 0.79 | SERPINE1 (0.37) | ATMSERPINE1 | |
| SCHEMBL3188398 | 0.78 | EDNRA (0.46) | ATMSERPINE1EDNRAMEN1KMT2A | |
| SCHEMBL3188408 | 0.78 | EDNRA (0.46) | ATMSERPINE1EDNRAMEN1KMT2A | |
| SCHEMBL4781594 | 0.75 | ATM (0.37) | ATMSERPINE1EDNRAMEN1KMT2A | |
| SCHEMBL4781593 | 0.75 | ATM (0.37) | ATMSERPINE1EDNRAMEN1KMT2A | |
| SCHEMBL5854242 | 0.74 | ATM (0.35) | ATMSERPINE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420853-B2 | Derivatives of cyclic compound and the use thereof | Wonkisopharm Co., Ltd (KR) | 2013-04-16 | — | — | US | disclosed |
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | disclosed |