Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17009549 | 0.84 | CYP2D6 (0.36) | CYP4F2CYP4A11ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL4763096 | 0.83 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1CYP2D6MEN1 | |
| SCHEMBL20533579 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1CYP2D6MEN1 | |
| SCHEMBL1274563 | 0.81 | CYP4F2 (0.34) | CYP4F2CYP4A11ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL1503918 | 0.80 | — | — | |
| SCHEMBL4132172 | 0.80 | POLB (0.44) | ALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL21807700 | 0.80 | CYP4F2 (0.33) | CYP4F2CYP4A11ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL15437385 | 0.80 | JAK2 (0.34) | CYP4F2CYP4A11ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL1274527 | 0.80 | CYP4F2 (0.33) | CYP4F2CYP4A11CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL14249923 | 0.80 | POLB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016676-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | disclosed |