Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772531 | 0.90 | POLB (0.41) | MAPTL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL4773797 | 0.88 | POLB (0.41) | MAPTL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL4769171 | 0.87 | POLB (0.40) | MAPTL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL4771569 | 0.87 | POLB (0.40) | MAPTL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL3172845 | 0.86 | POLB (0.42) | MAPTL3MBTL1ALDH1A1TDP1HTT | |
| SCHEMBL4776141 | 0.83 | POLB (0.43) | MAPTALDH1A1TDP1SMN1; SMN2POLB | |
| SCHEMBL4011042 | 0.82 | TOP2A (0.46) | MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28761871 | 0.81 | POLB (0.39) | MAPTL3MBTL1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL13527456 | 0.80 | POLB (0.42) | MAPTALDH1A1TDP1MAPK1HTT | |
| SCHEMBL11804724 | 0.80 | MAPT (0.47) | MAPTL3MBTL1ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |