SCHEMBL477843

SCHEMBL477843

[CH]=CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5135 0.61
SCHEMBL11051275 0.58
SCHEMBL56 0.55
SCHEMBL9173302 0.55
SCHEMBL1760771 0.55
SCHEMBL529 0.55
SCHEMBL21834967 0.55
SCHEMBL21835043 0.55
SCHEMBL21072680 0.55
SCHEMBL15624 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12011444-B2 N-substituted indole derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-18 US claimed
CN-117263947-A Heterocyclic compound and application thereof 浙江八亿时空先进材料有限公司 2023-12-22 CN claimed
US-20230348384-A1 Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides UCB PHARMA GMBH (DE) 2023-11-02 US claimed
CN-116936737-A Sodium ion battery and preparation method and application thereof 华为技术有限公司 2023-10-24 CN claimed
WO-2023186165-A1 SODIUM-ION BATTERY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 华为技术有限公司 2023-10-05 WO claimed
US-20230303584-A1 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF CIT THERAPEUTICS LLC 2023-09-28 US claimed
CN-111725563-B Non-aqueous electrolyte of lithium ion battery and lithium ion battery 诺莱特电池材料(苏州)有限公司 2023-09-15 CN claimed
CN-116621836-A Carbazole derivative and application thereof 北京八亿时空液晶科技股份有限公司 2023-08-22 CN claimed
CN-116425668-A Carbazole derivative and application thereof 北京八亿时空液晶科技股份有限公司 2023-07-14 CN claimed
CN-116023374-A Heterocyclic compound and application thereof 北京八亿时空液晶科技股份有限公司 2023-04-28 CN claimed
US-6498180-B1 SUCH AS 2-(3'-HYDROXYMETHYL-2'-CARBOXYCYCLOPROPYL)GLYCINE; MODULATING METABOTROPIC GLUTAMATE RECEPTOR; TREATING DISORDERS OF CENTRAL NERVOUS ELI LILLY AND COMPANY 2002-12-24 US claimed
EP-1189873-A1 EXCITATORY AMINO ACID RECEPTOR MODULATORS Lilly, S.A. (ES) 2002-03-27 EP claimed
WO-2000075101-A1 EXCITATORY AMINO ACID RECEPTOR MODULATORS LILLY, S.A. (ES) 2000-12-14 WO claimed
US-6037339-A METHOD FOR TREATING OSTEOPOROSIS AKZO NOBEL N.V. (NL) 2000-03-14 US claimed
EP-0682672-A1 STEROIDS FOR TREATING MENOPAUSAL COMPLAINTS Akzo Nobel N.V. (NL) 1995-11-22 EP claimed
WO-1994018224-A1 STEROIDS FOR TREATING MENOPAUSAL COMPLAINTS AKZO NOBEL N.V. (NL) 1994-08-18 WO claimed
US-5120849-A Reacting cyclic imidoether with aminoalcohol BASF AKTIENGESELLSCHAFT (DE) 1992-06-09 US claimed
US-5049551-A Antitumor UBE INDUSTRIES, LTD. (JP) 1991-09-17 US claimed
EP-0433749-A2 Pyrazolin-5-on-derivatives BAYER AG (DE) 1991-06-26 EP claimed
EP-0400610-A1 5-Fluorouracil derivatives UBE INDUSTRIES, LTD. (JP) 1990-12-05 EP claimed