Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.34 |
| ▸ | GBA1 | P04062 | 4/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417988 | 1.00 | CHRM1 (0.41) | CHRM1BCHEMAN1B1CHRNB2CHRNA4 | |
| SCHEMBL19212123 | 0.79 | CHRM1 (0.40) | CHRM1BCHECHRNB2CHRNA4CHRNA7 | |
| SCHEMBL5231114 | 0.78 | MAN1B1 (0.42) | CHRM1MAN1B1FUCA1GBA1GLA | |
| SCHEMBL5230075 | 0.78 | MAN1B1 (0.42) | CHRM1MAN1B1FUCA1GBA1GLA | |
| SCHEMBL14655735 | 0.75 | MAN1B1 (0.43) | MAN1B1FUCA1GBA1GLAGAA | |
| SCHEMBL4194315 | 0.75 | — | — | |
| SCHEMBL4128815 | 0.75 | CHRM1 (0.37) | CHRM1BCHECHRNB2CHRNA4CHRNA7 | |
| SCHEMBL4128819 | 0.75 | CHRM1 (0.37) | CHRM1BCHECHRNB2CHRNA4CHRNA7 | |
| SCHEMBL3714961 | 0.74 | GBA1 (0.33) | GBA1 | |
| SCHEMBL14690436 | 0.74 | MAN1B1 (0.42) | MAN1B1FUCA1GBA1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |