Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303026 | 0.91 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4297655 | 0.89 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4778673 | 0.88 | KCNH2 (0.52) | KCNH2NR1H4HTR2A | |
| SCHEMBL4296642 | 0.88 | KCNH2 (0.54) | KCNH2NR1H4HTR2A | |
| SCHEMBL10313895 | 0.88 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL4294604 | 0.86 | KCNH2 (0.42) | KCNH2NR1H4HTR2A | |
| SCHEMBL4304741 | 0.85 | KCNH2 (0.44) | KCNH2NR1H4HTR2A | |
| SCHEMBL10313961 | 0.85 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL4775985 | 0.84 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL4775750 | 0.84 | KCNH2 (0.48) | KCNH2NR1H4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |