Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859391 | 0.96 | KCNA3 (0.42) | KCNA3CCNT1CDK9MCHR1KCNH2 | |
| SCHEMBL3843908 | 0.88 | KCNA3 (0.43) | KCNA3DRD3DRD2PLK1HTR7 | |
| SCHEMBL4301542 | 0.88 | CNR2 (0.45) | MCHR1KCNH2DRD3ALDH1A1CCR3 | |
| SCHEMBL3839979 | 0.86 | MCHR1 (0.44) | MCHR1KCNH2DRD3DRD2ALDH1A1 | |
| SCHEMBL4302247 | 0.86 | KCNA3 (0.49) | KCNA3KCNH2DRD2PLK1CNR2 | |
| SCHEMBL12002142 | 0.81 | KCNH2 (0.49) | KCNA3KCNH2NPY5R | |
| SCHEMBL4303624 | 0.80 | HTR2C (0.43) | CDK9DRD2 | |
| SCHEMBL13234465 | 0.79 | KCNH2 (0.46) | KCNA3KCNH2DRD3DRD2CNR2 | |
| SCHEMBL4300063 | 0.78 | CNR2 (0.48) | MCHR1KCNH2DRD3DRD2CCR3 | |
| SCHEMBL5021645 | 0.78 | KCNH2 (0.55) | KCNA3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |