⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858174 | 0.90 | — | — | |
| SCHEMBL7858169 | 0.87 | MAPT (0.31) | — | |
| SCHEMBL465854 | 0.77 | — | — | |
| SCHEMBL13719307 | 0.76 | — | — | |
| SCHEMBL13719304 | 0.76 | — | — | |
| SCHEMBL13718881 | 0.76 | — | — | |
| SCHEMBL2418524 | 0.74 | — | — | |
| SCHEMBL1721187 | 0.73 | — | — | |
| SCHEMBL3086208 | 0.72 | MAPT (0.32) | — | |
| SCHEMBL7858254 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348421-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | LUYE INNOMIND PHARMA SHIJIAZHUANG CO., LTD. (CN) | 2023-11-02 | — | — | US | claimed |
| EP-4186893-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Geneora Pharma (Shijiazhuang) Co., Ltd. (CN) | 2023-05-31 | — | — | EP | claimed |
| CN-114728933-A | 5-HT2AReceptor inhibitor or inverse agonist, preparation method and application thereof | 山东绿叶制药有限公司 | 2022-07-08 | — | — | CN | claimed |
| US-20230348421-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | LUYE INNOMIND PHARMA SHIJIAZHUANG CO., LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| CN-114728933-B | 5-HT 2A Receptor inhibitor or inverse agonist, preparation method and application thereof | 山东绿叶制药有限公司 | 2023-06-16 | — | — | CN | disclosed |
| EP-4186893-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Geneora Pharma (Shijiazhuang) Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |
| CN-115850204-A | Tetrahydrobenzothiophene derivative and preparation method and application thereof | 烟台大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115052856-A | 3-alkoxybenzamide derivative and pest control agent | 组合化学工业株式会社 | 2022-09-13 | — | — | CN | disclosed |
| EP-3303305-B9 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2022-07-13 | — | — | EP | disclosed |
| CN-114728933-A | 5-HT2AReceptor inhibitor or inverse agonist, preparation method and application thereof | 山东绿叶制药有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3943486-A1 | 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES | FMC Corporation (US) | 2022-01-26 | — | — | EP | disclosed |
| EP-0352123-B1 | 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use | UBE INDUSTRIES (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5348961-A | Antibacterial agents | SANKYO COMPANY LIMITED (JP) | 1994-09-20 | — | — | US | disclosed |
| EP-0610958-A2 | Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5270327-A | Piperidine derivatives | SANKYO COMPANY, LIMITED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0356247-B1 | ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES | Sankyo Company Limited (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5073556-A | Bactericides | SANKYO COMPANY LIMITED (JP) | 1991-12-17 | — | — | US | disclosed |
| US-5021413-A | Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0356247-A1 | Analgesic carboxylic acid amide derivatives | Sankyo Company Limited (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0352123-A2 | 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use | UBE INDUSTRIES LIMITED (JP) | 1990-01-24 | — | — | EP | disclosed |