⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475047 | 0.82 | — | — | |
| SCHEMBL15404393 | 0.73 | — | — | |
| SCHEMBL15403928 | 0.73 | — | — | |
| SCHEMBL20688 | 0.72 | — | — | |
| SCHEMBL18632255 | 0.72 | — | — | |
| SCHEMBL2487471 | 0.72 | — | — | |
| SCHEMBL17891899 | 0.72 | — | — | |
| SCHEMBL10635 | 0.70 | — | — | |
| SCHEMBL19736 | 0.70 | — | — | |
| SCHEMBL8740281 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 707 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849664-B1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2024-06-12 | — | — | EP | claimed |
| EP-3849663-B1 | PYRIMIDINYL-HETEROARYLOXY-NAPHTHYL COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2023-08-02 | — | — | EP | claimed |
| WO-2023139084-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | claimed |
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2023-02-23 | — | — | US | claimed |
| CN-108218849-B | Novel inhibitors | 维沃永治疗公众有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-3328379-B1 | BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION | UCB Biopharma SRL (BE) | 2021-07-28 | — | — | EP | claimed |
| EP-3849664-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | Genentech, Inc. (US) | 2021-07-21 | — | — | EP | claimed |
| CN-112689528-A | Pyrimidinyl-heteroaryloxy-naphthyl compounds and methods of use | 基因泰克公司 | 2021-04-20 | — | — | CN | claimed |
| WO-2020056089-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2020-03-19 | — | — | WO | claimed |
| EP-2970235-B1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2019-06-19 | — | — | EP | claimed |
| US-3993687-A | ANTIULCER, INHIBITION OF PLATELET AGGREGATION | THE UPJOHN COMPANY (US) | 1976-11-23 | — | — | US | claimed |
| US-3988361-A | HYPOTENSIVE AGENTS, ANTILIPOLYTIC AGENTS; PROSTAGLANDIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1976-10-26 | — | — | US | claimed |
| US-3987083-A | ANTIULCER, ANTICOAGULANTS, ABORTION, DECONGESTANTS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | claimed |
| US-3983155-A | Racemic prostaglandins of the 2-series and analogs thereof | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | claimed |
| US-3983153-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | claimed |
| US-3983154-A | Racemic prostaglandins of the 2-series and analogs thereof | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | claimed |
| US-3981880-A | ANTIULCER, ANTICOAGULANT, WOUND HEALING, ABORTION | THE UPJOHN COMPANY (US) | 1976-09-21 | — | — | US | claimed |
| US-3980691-A | ANTIULCER, INHIBITION OF PLATELET AGGRESSION, INCREASE OF NASAL PATENCY, ABORTION, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-09-14 | — | — | US | claimed |
| US-3974200-A | ANTIULCER, INHIBIT PLATELET AGGREGATION, NASAL PATENCY, ABORTION, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-08-10 | — | — | US | claimed |
| US-3959346-A | Racemic prostaglandins of the 2-series and analogs thereof | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | claimed |