Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587540 | 0.92 | NPSR1 (0.68) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL3588145 | 0.90 | NPSR1 (0.63) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL3589670 | 0.86 | NPSR1 (0.60) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL3593253 | 0.83 | NPSR1 (0.59) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL3592325 | 0.83 | NPSR1 (0.62) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL3596025 | 0.83 | NPSR1 (0.61) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL3588168 | 0.83 | NPSR1 (0.61) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL14547095 | 0.83 | NPSR1 (0.56) | NPSR1GFERHSD17B10KDM4EALDH1A1 | |
| SCHEMBL3593438 | 0.81 | GFER (0.55) | NPSR1GFERHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL14160313 | 0.81 | GFER (0.58) | NPSR1GFERHSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007036730-A9 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LTD (GB) | 2008-06-19 | — | — | WO | disclosed |