Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.72 |
| ▸ | MAPT | P10636 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | PLK4 | O00444 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148621 | 0.90 | MEN1 (0.81) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL31615276 | 0.88 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL25808114 | 0.87 | MEN1 (0.77) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL4024926 | 0.85 | MEN1 (0.74) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL30523171 | 0.85 | MEN1 (0.74) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5239415 | 0.84 | KDM4E (1.00) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL14258765 | 0.84 | KMT2A (0.72) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5583148 | 0.83 | KDM4E (0.98) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL12868475 | 0.82 | HSD17B10 (1.00) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL31615263 | 0.81 | MAPT (1.00) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |