Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.74 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.62 |
| ▸ | AKT2 | P31751 | 1/20 | 0.62 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918042 | 0.92 | AKT1 (0.77) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4780211 | 0.92 | AKT1 (0.87) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4778636 | 0.92 | AKT1 (0.77) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4776360 | 0.92 | AKT1 (0.81) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4921225 | 0.90 | AKT1 (0.76) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4916462 | 0.89 | AKT1 (0.77) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4778598 | 0.89 | AKT1 (0.71) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4725191 | 0.89 | AKT1 (0.70) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4916364 | 0.88 | AKT1 (0.73) | AKT1RPS6KB1AKT2AKT3 | |
| SCHEMBL4776999 | 0.88 | AKT1 (0.75) | AKT1RPS6KB1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012635-A2 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |