Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE11A | Q9HCR9 | 13/20 | 0.72 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729879 | 0.86 | PDE11A (0.76) | PDE11A | |
| SCHEMBL4725887 | 0.86 | PDE11A (0.84) | PDE11APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4780206 | 0.83 | PDE11A (1.00) | PDE11APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4727795 | 0.83 | PDE11A (0.84) | PDE11APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4725308 | 0.83 | PDE11A (0.81) | PDE11A | |
| SCHEMBL4728040 | 0.83 | PDE11A (0.81) | PDE11APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4729299 | 0.82 | PDE11A (0.80) | PDE11A | |
| SCHEMBL4779597 | 0.81 | PDE11A (0.78) | PDE11APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4729789 | 0.81 | PDE11A (0.69) | PDE11A | |
| SCHEMBL4726024 | 0.81 | PDE11A (0.55) | PDE11APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020711-A1 | QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-02-21 | — | — | WO | claimed |
| WO-2008020711-A1 | QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-02-21 | — | — | WO | disclosed |