Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.65 |
| ▸ | PPARG | P37231 | 6/20 | 0.65 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057848 | 1.00 | PPARA (0.65) | PPARAPPARGPPARDFFAR1LMNA | |
| SCHEMBL5994086 | 0.81 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5365635 | 0.81 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5999342 | 0.81 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5992494 | 0.80 | PPARA (0.61) | PPARAPPARGPPARDFFAR1L3MBTL1 | |
| Tesaglitazar SCHEMBL16594 | 0.79 | PPARA (1.00) | PPARAPPARGPPARD | |
| Tesaglitazar SCHEMBL13602606 | 0.79 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5368994 | 0.79 | PPARA (1.00) | PPARAPPARGPPARD | |
| Tesaglitazar SCHEMBL3162078 | 0.79 | PPARA (1.00) | PPARAPPARGPPARD | |
| Tesaglitazar SCHEMBL600880 | 0.79 | PPARA (1.00) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093747-A3 | USE OF TESAGLITIZAR FOR PREPARING A PHARMACEUTICAL COMPOSITION FOR TREATING SKIN DISORDERS | GALDERMA RES & DEV (FR) | 2008-01-17 | — | — | WO | disclosed |
| WO-2007093747-A2 | USE OF TESAGLITIZAR FOR PREPARING A PHARMACEUTICAL COMPOSITION FOR TREATING SKIN DISORDERS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-08-23 | — | — | WO | disclosed |