Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 17/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | TACR2 | P21452 | 4/20 | 0.64 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667527 | 0.93 | TACR3 (0.72) | TACR3CYP2C9TACR2TRPV4 | |
| SCHEMBL4665928 | 0.92 | TACR3 (0.71) | TACR3CYP2C9TACR2TRPV4 | |
| SCHEMBL8267598 | 0.85 | TACR3 (0.78) | TACR3CYP2C9 | |
| SCHEMBL4887319 | 0.84 | TACR3 (0.67) | TACR3CYP2C9TACR2TRPV4 | |
| SCHEMBL4887323 | 0.84 | TACR3 (0.67) | TACR3CYP2C9TACR2TRPV4 | |
| SCHEMBL4668623 | 0.84 | TACR3 (0.67) | TACR3CYP2C9TACR2 | |
| SCHEMBL4989018 | 0.83 | TACR3 (0.75) | TACR3CYP2C9 | |
| SCHEMBL4989012 | 0.83 | TACR3 (0.75) | TACR3CYP2C9 | |
| SCHEMBL1580871 | 0.83 | CYP2C9 (0.76) | TACR3CYP2C9 | |
| SCHEMBL4898683 | 0.82 | TACR3 (0.68) | TACR3CYP2C9TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940795-A1 | N-OXO-HETEROCYCLE AND N-OXO-ALKYL QUINOLINE-4-CARBOXAMIDES AS NK-3 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2008-07-09 | — | — | EP | claimed |
| WO-2007035156-A1 | N-OXO-HETEROCYCLE AND N-OXO-ALKYL QUINOLINE-4-CARBOXAMIDES AS NK-3 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2007-03-29 | — | — | WO | claimed |