Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114695 | 0.84 | TSHR (0.66) | ALDH1A1TSHRAPLNRKMT2APDCD1 | |
| SCHEMBL18765477 | 0.83 | PDCD1 (0.63) | ALDH1A1TSHRAPLNRKMT2APDCD1 | |
| Hydrochloric Acid SCHEMBL31580079 | 0.83 | TSHR (0.64) | ALDH1A1TSHRAPLNRKMT2APDCD1 | |
| SCHEMBL31114359 | 0.82 | TSHR (0.67) | ALDH1A1TSHRAPLNRKMT2APOLB | |
| SCHEMBL3919386 | 0.82 | TSHR (0.71) | ALDH1A1TSHRAPLNRKMT2APOLB | |
| Hydrochloric Acid SCHEMBL11688129 | 0.79 | TSHR (0.67) | ALDH1A1TSHRAPLNRKMT2APOLB | |
| SCHEMBL21603925 | 0.79 | TSHR (0.56) | ALDH1A1TSHRAPLNRKMT2APDCD1 | |
| SCHEMBL21603927 | 0.79 | TSHR (0.56) | ALDH1A1TSHRAPLNRKMT2APDCD1 | |
| SCHEMBL4618413 | 0.78 | TSHR (0.59) | ALDH1A1TSHRAPLNRKMT2APDCD1 | |
| SCHEMBL14207884 | 0.78 | TSHR (0.59) | ALDH1A1TSHRAPLNRKMT2APDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |