Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337044 | 0.72 | — | — | |
| SCHEMBL28109478 | 0.72 | — | — | |
| SCHEMBL325976 | 0.67 | — | — | |
| SCHEMBL31194320 | 0.64 | — | — | |
| SCHEMBL28514773 | 0.64 | TSHR (0.50) | TSHRTDP1 | |
| SCHEMBL28519072 | 0.64 | TSHR (0.50) | TSHRTDP1 | |
| SCHEMBL754926 | 0.63 | — | — | |
| Propane SCHEMBL297421 | 0.62 | TSHR (0.73) | TSHRTDP1 | |
| SCHEMBL3146161 | 0.61 | — | — | |
| SCHEMBL28936219 | 0.61 | TSHR (0.47) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877470-B1 | BICYCLIC AZA-AMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V (DE) | 2017-09-13 | — | — | EP | disclosed |
| WO-2008025796-A1 | BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM | TREOFAN GERMANY GMBH & CO. KG (DE) | 2008-03-06 | — | — | WO | disclosed |