Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CCR2 | P41597 | 17/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306923 | 0.91 | CYP2C9 (0.46) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL306821 | 0.84 | CYP2C9 (0.53) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL10223462 | 0.82 | CYP2C9 (0.55) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL306593 | 0.81 | CYP2C9 (0.53) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL306303 | 0.79 | CYP2C9 (0.56) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL306330 | 0.78 | CYP2C9 (0.53) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL29888405 | 0.78 | CYP2C9 (0.53) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL305517 | 0.78 | CYP2C9 (0.53) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL306097 | 0.77 | CYP2C9 (0.57) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL306130 | 0.76 | CYP2C9 (0.55) | CYP2C9CCR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008431-A2 | HETEROARYL SULFONAMIDES AND CCR2/CCR9 | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |