Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21218008 | 0.87 | CA1 (0.55) | CA1CA2CA9DGAT1P4HB | |
| SCHEMBL16899438 | 0.84 | CA1 (0.50) | CA1CA2CA9DGAT1P4HB | |
| SCHEMBL14242308 | 0.84 | CA9 (0.60) | CA1CA2CA9P4HBLPL | |
| SCHEMBL19418254 | 0.82 | CA1 (0.62) | CA1CA2CA9P4HBLPL | |
| SCHEMBL15648726 | 0.81 | CA1 (0.61) | CA1CA2CA9P4HBLPL | |
| SCHEMBL16183487 | 0.81 | CA1 (0.61) | CA1CA2CA9P4HBLPL | |
| SCHEMBL15552116 | 0.81 | CA1 (0.53) | CA1CA2CA9DGAT1P4HB | |
| SCHEMBL1128752 | 0.80 | CA1 (0.59) | CA1CA2CA9P4HBLPL | |
| SCHEMBL17645779 | 0.80 | CA1 (0.69) | CA1CA2CA9 | |
| SCHEMBL15550654 | 0.80 | CA1 (0.56) | CA1CA2CA9P4HBLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |