Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436162 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL28016022 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL19287165 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL8204966 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL2160625 | 1.00 | TSHR (0.54) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL4912351 | 0.98 | — | — | |
| SCHEMBL9007954 | 0.96 | TSHR (0.50) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL5255821 | 0.93 | — | — | |
| SCHEMBL29128731 | 0.90 | — | — | |
| SCHEMBL16568619 | 0.85 | TSHR (0.50) | TSHRFAAHTRPV1HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004130-A2 | PEPTIDES FOR TARGETING THE MITOCHONDRIAL TRANSITION PORE COMPLEX FOR THERAPEUTIC APOPTOSIS INDUCTION AND BIOLOGICAL APPLICATIONS | THERAPTOSIS S.A. (FR) | 2008-01-10 | — | — | WO | claimed |