Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781074 | 0.83 | MCHR1 (0.45) | MCHR1KCNH2HTR2CDRD3DRD2 | |
| SCHEMBL4793451 | 0.82 | MCHR1 (0.46) | CA1CA2ACHEMCHR1KCNH2 | |
| SCHEMBL4795364 | 0.81 | CA1 (0.41) | CA1CA2ACHEMCHR1KCNH2 | |
| SCHEMBL4794873 | 0.80 | CA1 (0.40) | CA1CA2ACHEMCHR1KCNH2 | |
| SCHEMBL5935178 | 0.79 | CA1 (0.39) | CA1CA2ACHEMCHR1KCNH2 | |
| SCHEMBL4779652 | 0.78 | CA1 (0.41) | CA1CA2ACHEMCHR1KCNH2 | |
| SCHEMBL4792237 | 0.77 | CA1 (0.40) | CA1CA2ACHEMCHR1KCNH2 | |
| SCHEMBL4794027 | 0.76 | HTR1D (0.43) | CA1CA2ACHEDRD3DRD2 | |
| SCHEMBL4778928 | 0.76 | HRH3 (0.50) | CA1CA2ACHEMCHR1KCNH2 | |
| SCHEMBL4796188 | 0.75 | DRD3 (0.45) | CA1CA2ACHEDRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247239-A1 | Melanin concentrating hormone antagonists | HU XIUFENG E | 2006-11-02 | — | — | US | claimed |
| WO-2008001160-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |
| US-20060247239-A1 | Melanin concentrating hormone antagonists | HU XIUFENG E | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247239-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | CA1 3371/4885CA2 1850/4885ACHE 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.