Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 14/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644542 | 0.81 | CHRM3 (0.72) | CHRM3CHRM2CHRM1LMNA | |
| SCHEMBL143799 | 0.81 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL143800 | 0.81 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4779801 | 0.78 | CHRM3 (0.74) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1009534 | 0.67 | CHRM3 (0.74) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1009533 | 0.67 | CHRM3 (0.74) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1009920 | 0.66 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1009919 | 0.66 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6703364 | 0.66 | CHRM3 (0.38) | CHRM3CHRM2CHRM1 | |
| SCHEMBL139738 | 0.65 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008000777-A2 | PHENYL- PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | GLAXO GROUP LIMITED (GB) | 2008-01-03 | — | — | WO | disclosed |
| EP-1802658-A2 | CHIMERIC AND HUMANISED MONOCLONAL ANTIBODIES AGAINST INTERLEUKIN-13 | GLAXO GROUP LIMITED (GB) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006003407-A2 | CHIMERIC AND HUMANISED MONOCLONAL ANTIBODIES AGAINST INTELEUKIN- 13 | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |