Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.59 |
| ▸ | CNR2 | P34972 | 6/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537283 | 0.92 | CNR1 (0.55) | CNR1CNR2CYP19A1PTGS2PDE5A | |
| SCHEMBL2544881 | 0.91 | CNR1 (0.51) | CNR1CNR2PDE5AMEN1KMT2A | |
| SCHEMBL2545396 | 0.90 | CNR1 (0.51) | CNR1CNR2CCR1CCR2MAPT | |
| SCHEMBL13241586 | 0.89 | CNR1 (0.48) | CNR1CNR2CYP19A1PDE5AMEN1 | |
| SCHEMBL2536936 | 0.89 | CNR1 (0.50) | CNR1CNR2CYP19A1PTGS2PDE5A | |
| SCHEMBL2539861 | 0.89 | CNR1 (0.48) | CNR1CNR2CCR1L3MBTL1 | |
| SCHEMBL2537482 | 0.89 | CNR1 (0.49) | CNR1CNR2PDE5AMEN1KMT2A | |
| SCHEMBL2537487 | 0.89 | CNR1 (0.49) | CNR1CNR2PDE5AMEN1KMT2A | |
| SCHEMBL2539927 | 0.89 | CNR1 (0.49) | CNR1CNR2PDE5AMEN1KMT2A | |
| SCHEMBL2540544 | 0.88 | CNR1 (0.51) | CNR1CNR2CYP19A1PTGS2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |