Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.62 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RORC | P51449 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725105 | 0.86 | NPY5R (1.00) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4725755 | 0.85 | NPY5R (0.98) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4727176 | 0.84 | NPY5R (0.80) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4725254 | 0.84 | MAPT (0.85) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4727570 | 0.84 | NPY5R (1.00) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4725128 | 0.82 | NPY5R (0.79) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4725717 | 0.81 | NPY5R (0.78) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4727182 | 0.80 | NPY5R (0.76) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4725633 | 0.80 | NPY5R (0.70) | NPY5RKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4730111 | 0.80 | NPY5R (0.75) | NPY5RKDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |