Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217909 | 0.90 | PTPN1 (0.45) | PTPN1CNR1CNR2POLBHTT | |
| SCHEMBL2930641 | 0.89 | PTPN1 (0.44) | PTPN1CNR1CNR2MEN1KMT2A | |
| SCHEMBL3214738 | 0.88 | PTPN1 (0.47) | PTPN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL2929598 | 0.85 | PTPN1 (0.44) | PTPN1CNR1CNR2MEN1KMT2A | |
| SCHEMBL3217863 | 0.82 | PTPN1 (0.46) | PTPN1CNR1CNR2MAPTPOLB | |
| SCHEMBL3226821 | 0.82 | PTPN1 (0.43) | PTPN1CNR1CNR2LIPG | |
| SCHEMBL3216194 | 0.81 | PTPN1 (0.42) | PTPN1MEN1KMT2ASMN1; SMN2LIPG | |
| SCHEMBL3220375 | 0.81 | PTPN1 (0.41) | PTPN1CNR1CNR2MEN1KMT2A | |
| SCHEMBL3216067 | 0.81 | CNR1 (0.42) | PTPN1CNR1CNR2POLBHTT | |
| SCHEMBL3222948 | 0.79 | PTPN1 (0.41) | PTPN1CNR1CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008067527-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS | NOVARTIS AG (CH) | 2008-06-05 | — | — | WO | disclosed |