SCHEMBL4782196

SCHEMBL4782196

C[C@@H](C#N)OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.43
TSHR P16473 1/20 0.43
CTSL P07711 3/20 0.40
CTSB P07858 3/20 0.40
CTSK P43235 3/20 0.40
CTSS P25774 2/20 0.40
IDO1 P14902 1/20 0.40
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
SGMS2 Q8NHU3 2/20 0.40
MAPT P10636 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4730931 1.00 MAOB (0.43) MAOBTSHRCTSLCTSBCTSK
SCHEMBL24066351 0.81 RCE1 (0.47) MAOBTSHRCTSLCTSBCTSK
SCHEMBL23875054 0.81 RCE1 (0.47) MAOBTSHRCTSLCTSBCTSK
SCHEMBL28499564 0.80 MAOB (0.43) MAOBTSHRIDO1SLC1A3SLC1A2
SCHEMBL28499565 0.80 MAOB (0.43) MAOBTSHRIDO1SLC1A3SLC1A2
SCHEMBL6239307 0.80 SLC1A3 (0.43) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL6141169 0.80 SLC1A3 (0.43) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL31059752 0.80 MAOB (0.43) MAOBTSHRIDO1SLC1A3SLC1A2
SCHEMBL27900596 0.79 CYP3A4 (0.50) MAOBTSHRCTSBCTSKCTSS
SCHEMBL27667900 0.78 MAOB (0.42) MAOBTSHRCTSLCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644334-B1 ANTITHROMBOTIC ETHERS LILLY CO ELI (US) 2008-01-02 EP claimed