Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.57 |
| ▸ | CDK1 | P06493 | 2/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.57 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565947 | 0.98 | KDM4E (0.61) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL14115608 | 0.88 | KDM4E (0.63) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL26670160 | 0.84 | CYP19A1 (0.47) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL21566048 | 0.83 | CLK2 (0.52) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL21565988 | 0.82 | CYP19A1 (0.50) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL27075650 | 0.82 | CYP19A1 (0.53) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL22021633 | 0.81 | NPY5R (0.51) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL21566047 | 0.80 | CYP19A1 (0.47) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL6282533 | 0.79 | KDM4E (0.47) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL7945775 | 0.79 | KDM4E (0.73) | KDM4ENPC1RAB9AMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |