Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 19/20 | 0.58 |
| ▸ | PLK3 | Q9H4B4 | 16/20 | 0.58 |
| ▸ | PLK2 | Q9NYY3 | 15/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794798 | 0.90 | PLK1 (0.64) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL4783982 | 0.89 | PLK1 (0.65) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL4783698 | 0.85 | PLK1 (0.56) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL4780611 | 0.84 | PLK1 (0.68) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL3548082 | 0.84 | PLK1 (0.58) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL4732160 | 0.84 | PLK1 (0.78) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL4784171 | 0.84 | PLK1 (0.61) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL4780453 | 0.83 | PLK1 (0.62) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL4793942 | 0.83 | PLK1 (0.71) | PLK1PLK3PLK2BRD4 | |
| SCHEMBL3543367 | 0.82 | PLK1 (0.61) | PLK1PLK3PLK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040951-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2008-04-10 | — | — | WO | disclosed |