Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 6/20 | 0.48 |
| ▸ | ESR2 known ✓ | Q92731 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.69 |
| ▸ | CA1 | P00915 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | CA3 | P07451 | 2/20 | 0.69 |
| ▸ | CA4 | P22748 | 2/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL9331064 | 1.00 | CA12 (0.69) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL11206985 | 1.00 | CA12 (0.69) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL10433598 | 1.00 | CA12 (0.69) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL29392457 | 1.00 | CA12 (0.69) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL10886697 | 1.00 | CA12 (0.69) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL30505287 | 0.97 | CA12 (0.65) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL11609346 | 0.97 | CA12 (0.65) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL20798197 | 0.97 | CA12 (0.65) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL28202803 | 0.94 | CA12 (0.61) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL726343 | 0.94 | CA12 (0.69) | CA12CA1CA2CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 453 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655365-A1 | LUBRICATING COMPOSITION WITH PHENOLIC ANTIOXIDANT AND LOW ACTIVE SULFUR | The Lubrizol Corporation (US) | 2025-12-03 | — | — | EP | claimed |
| CN-119564549-A | Avocado cleansing cream containing modified avocado oil additive | 上海正喧品牌管理有限公司 | 2025-03-07 | — | — | CN | claimed |
| WO-2025024623-A1 | LUBRICATING COMPOSITION WITH PHENOLIC ANTIOXIDANT, CALCIUM SALICYLATE DETERGENT, AND LOW ACTIVE SULFUR | THE LUBRIZOL CORPORATION (US) | 2025-01-30 | — | — | WO | claimed |
| WO-2024158648-A1 | LUBRICATING COMPOSITION WITH PHENOLIC ANTIOXIDANT AND LOW ACTIVE SULFUR | THE LUBRIZOL CORPORATION (US) | 2024-08-02 | — | — | WO | claimed |
| CN-118388325-A | Preparation method of 1-naphthol compound | 西北工业大学 | 2024-07-26 | — | — | CN | claimed |
| CN-115612126-B | Crosslinked polystyrene solid acid catalyst with polymerization inhibition function, and preparation method and application thereof | 江苏集萃光敏电子材料研究所有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-115300565-A | Application of pharmaceutical composition in treating or preventing autoimmune liver injury | 常熟雷允上制药有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-113777204-B | Detection method of p-hydroxyacetophenone related substances | 河北广祥制药有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-113777204-A | Detection method of p-hydroxyacetophenone related substances | 河北广祥制药有限公司 | 2021-12-10 | — | — | CN | claimed |
| CN-113576995-A | Dendrobium anti-inflammation toothpaste and preparation method thereof | 四川干邦亚农业科技有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-101029041-A | Aryl-folinic phenol acetic acid and 1,4-dioxane complex, its production and use | YINGLI SCIENCE & TECHNOLOGY DE (CN) | 2007-09-05 | — | — | CN | claimed |
| CN-1451009-A | Glucocortiocoid-selective antinflammatory agents | ABBOTT LAB (US) | 2003-10-22 | — | — | CN | claimed |
| CN-1119348-C | glucocorticoid derivatives, compositions and uses thereof | ABBOTT INC (US) | 2003-08-27 | — | — | CN | claimed |
| EP-0925321-B1 | PREPOLYMERS CONTAINING MALEIMID FUNCTIONS, METHOD OF PRODUCING AND USE THEREOF | CRAY VALLEY SA (FR) | 2002-06-12 | — | — | EP | claimed |
| US-6306923-B1 | Ultraviolet or visible light polymerizable and/or crosslinkable maleimide-functional coating compositions | SARTOMER COMPANY, INC. | 2001-10-23 | — | — | US | claimed |
| CN-1308627-A | 11-Aryl-benzo[b]naphtho[2,3-d]furans and 11-aryl-aryl-benzo[b]anphtho[2,3-d]thiophenes useful in the treatment of insulin resistance and hyperglycemia | AMERICAN HOME PROD (US) | 2001-08-15 | — | — | CN | claimed |
| US-6271339-B1 | REACTING A MALEIMIDE WITH A PRIMARY AMINE HAVING AT LEAST ONE OTHER REACTIVE GROUP TO FORM A A MALEAMIC ACID, PARTIALLY CYCLIZING, AND REACTING PRODUCT WITH A POLYFUNCION COMPOUND. | SARTOMER COMPANY, INC. | 2001-08-07 | — | — | US | claimed |
| CN-1296486-A | Glucocorticoid-selective anti-inflammatory agents | ABBOTT LAB (US) | 2001-05-23 | — | — | CN | claimed |
| EP-0925320-B1 | COATING COMPOSITIONS POLYMERISABLE AND/OR CROSS-LINKABLE BY ULTRAVIOLET OR VISIBLE LIGHT | CRAY VALLEY SA (FR) | 2001-01-24 | — | — | EP | claimed |
| CN-1279228-A | Fertilizer for elongating green period of lawn | XIA NING (CN) | 2001-01-10 | — | — | CN | claimed |