Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782592 | 1.00 | FFAR1 (0.54) | FFAR1MAPTFFAR4 | |
| SCHEMBL4736863 | 0.86 | FFAR1 (0.68) | FFAR1MAPT | |
| SCHEMBL4736855 | 0.86 | FFAR1 (0.68) | FFAR1MAPT | |
| SCHEMBL4804081 | 0.78 | FFAR1 (0.75) | FFAR1MAPT | |
| SCHEMBL4804068 | 0.78 | FFAR1 (0.75) | FFAR1MAPT | |
| SCHEMBL4739724 | 0.78 | FFAR1 (0.61) | FFAR1FFAR4 | |
| SCHEMBL4737595 | 0.78 | FFAR1 (0.60) | FFAR1FFAR4 | |
| SCHEMBL4739732 | 0.78 | FFAR1 (0.61) | FFAR1FFAR4 | |
| SCHEMBL4740999 | 0.78 | FFAR1 (0.60) | FFAR1FFAR4 | |
| SCHEMBL4786197 | 0.75 | FFAR1 (0.55) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893582-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE IN TREATING METABOLIC DISORDERS | Amgen, Inc (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006127503-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE IN TREATING METABOLIC DISORDERS | AMGEN INC (US) | 2006-11-30 | — | — | WO | disclosed |