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SCHEMBL4782771

SCHEMBL4782771

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)N1CCN(C(=O)N(C)C)CC1.Cc1ccc(C(=O)N2CCC(c3ccc(C(F)(F)F)cc3)CC2)cc1NC(=O)NC1CCCN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FASN P49327 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199345 0.88 FASN (0.59) FASN
SCHEMBL4201374 0.88 HDAC4 (0.48) FASN
SCHEMBL4209401 0.83 FASN (0.58) FASN
SCHEMBL4196754 0.81 FASN (0.61) FASN
SCHEMBL4196797 0.81 FASN (0.63) FASN
SCHEMBL4210044 0.80 FASN (0.64) FASN
SCHEMBL4189321 0.79 FASN (0.65) FASN
SCHEMBL4195091 0.77 FASN (0.57) FASN
SCHEMBL4191319 0.77 FASN (0.46) FASN
SCHEMBL4194253 0.77 FASN (0.62) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 — — WO disclosed