Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.63 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.63 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.63 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.63 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.63 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739996 | 0.86 | EGLN1 (0.61) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL4993693 | 0.83 | EGLN1 (0.63) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL3422098 | 0.78 | EGLN1 (1.00) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL1641734 | 0.78 | EGLN1 (0.77) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL3419112 | 0.78 | EGLN1 (1.00) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL3421361 | 0.78 | EGLN1 (1.00) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL3423522 | 0.78 | EGLN1 (1.00) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL3422096 | 0.78 | EGLN1 (1.00) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| SCHEMBL3423425 | 0.77 | EGLN1 (0.97) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 | |
| Bicarbonate SCHEMBL15419071 | 0.77 | EGLN1 (0.97) | EGLN1HIF1ANOGFOD1EGLN2EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |