Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.85 |
| ▸ | CTSD | P07339 | 8/20 | 0.67 |
| ▸ | BACE2 | Q9Y5Z0 | 8/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926142 | 0.83 | BACE1 (0.76) | BACE1CTSDBACE2 | |
| SCHEMBL4528372 | 0.83 | BACE1 (0.76) | BACE1CTSDBACE2 | |
| SCHEMBL4783931 | 0.82 | BACE1 (0.82) | BACE1CTSDBACE2 | |
| SCHEMBL4785604 | 0.81 | BACE1 (0.85) | BACE1CTSDBACE2 | |
| SCHEMBL4785264 | 0.81 | BACE1 (0.62) | BACE1CTSDBACE2 | |
| SCHEMBL25916157 | 0.80 | BACE1 (1.00) | BACE1CTSDBACE2 | |
| SCHEMBL5136389 | 0.80 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL4308465 | 0.80 | BACE1 (1.00) | BACE1CTSDBACE2 | |
| SCHEMBL8238890 | 0.80 | BACE1 (0.78) | BACE1CTSDBACE2 | |
| SCHEMBL4315255 | 0.79 | BACE1 (0.77) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |