Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417751 | 1.00 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL4850686 | 0.92 | ESR2 (0.55) | ESR2ESR1 | |
| SCHEMBL2419519 | 0.90 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL2413921 | 0.90 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL2416708 | 0.89 | ESR1 (0.57) | ESR2ESR1 | |
| SCHEMBL2416756 | 0.89 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL2416223 | 0.88 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL5674441 | 0.88 | ESR2 (0.55) | ESR2ESR1 | |
| SCHEMBL5340411 | 0.88 | ESR2 (0.55) | ESR2ESR1 | |
| SCHEMBL2419393 | 0.86 | ESR2 (0.63) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247319-A1 | Preparation of 4-bromotetrahydrofluoreneones | HUFFMAN MARK A | 2006-11-02 | — | — | US | claimed |
| WO-2008057309-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008057309-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20060247319-A1 | Preparation of 4-bromotetrahydrofluoreneones | HUFFMAN MARK A | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247319-A1 | Preparation of 4-bromotetrahydrofluoreneones | CYP4F2, CYP4F3, CYP2F1 | ESR2 1605/4885ESR1 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.