Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.70 |
| ▸ | CNR1 | P21554 | 5/20 | 0.70 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733600 | 0.94 | CNR2 (0.76) | CNR2CNR1PDCD1CD274S1PR1 | |
| SCHEMBL4729591 | 0.90 | CNR2 (0.70) | CNR2CNR1S1PR1 | |
| SCHEMBL4729597 | 0.90 | CNR2 (0.70) | CNR2CNR1S1PR1 | |
| SCHEMBL4733598 | 0.88 | CNR2 (0.76) | CNR2CNR1S1PR1 | |
| SCHEMBL4732736 | 0.87 | CNR2 (0.66) | CNR2CNR1S1PR1 | |
| SCHEMBL4731819 | 0.85 | CNR2 (0.66) | CNR2CNR1S1PR1 | |
| SCHEMBL4730792 | 0.85 | CNR2 (0.82) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4732966 | 0.84 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4734554 | 0.84 | CNR2 (0.80) | CNR2CNR1PDCD1CD274 | |
| SCHEMBL4732902 | 0.83 | CNR2 (0.69) | CNR2CNR1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |