SCHEMBL4783526

SCHEMBL4783526

Cc1ccc(C(=O)N2CCC(c3cc(F)c(C#N)c(F)c3)CC2)cc1NS(C)(=O)=O.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)c(C#N)c3)CC2)cc1NS(C)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4183356 0.93 FASN (0.58) FASN
SCHEMBL4180107 0.92 FASN (0.61) FASN
SCHEMBL4170769 0.92 FASN (0.59) FASN
SCHEMBL4175763 0.88 FASN (0.62) FASN
SCHEMBL4181910 0.85 FASN (0.59) FASN
SCHEMBL4181166 0.84 FASN (0.56) FASN
SCHEMBL4181735 0.83 FASN (0.57) FASN
SCHEMBL4169825 0.81 FASN (0.78) FASN
SCHEMBL4183282 0.80 FASN (0.59) FASN
SCHEMBL4170238 0.79 FASN (0.66) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075070-A1 SULFONAMIDE DERIVATIVES FOR THERAPEUTIC USE AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-06-26 WO claimed