Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.57 |
| ▸ | CNR2 | P34972 | 5/20 | 0.57 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RNF114 | Q9Y508 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991907 | 0.93 | CNR1 (0.64) | CNR1CNR2EGFRNR3C2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2996363 | 0.92 | CNR1 (0.62) | CNR1CNR2EGFRNR3C2ALDH1A1 | |
| SCHEMBL2018962 | 0.90 | CNR1 (0.58) | CNR1CNR2EGFRNR3C2PDE5A | |
| SCHEMBL2020884 | 0.90 | CNR1 (0.58) | CNR1CNR2EGFRGABRA2GABRB2 | |
| SCHEMBL14396605 | 0.90 | CNR1 (0.58) | CNR1CNR2EGFRGABRA2GABRB2 | |
| SCHEMBL4607251 | 0.89 | CNR1 (0.57) | CNR1CNR2EGFRGABRA2GABRB2 | |
| Hydrochloric Acid SCHEMBL2020887 | 0.89 | CNR1 (0.57) | CNR1CNR2EGFRNR3C2PDE5A | |
| SCHEMBL14396247 | 0.89 | CNR1 (0.57) | CNR1CNR2EGFRNR3C2MAOB | |
| SCHEMBL2018106 | 0.86 | CNR1 (0.56) | CNR1CNR2EGFRGABRA2GABRB2 | |
| SCHEMBL2991729 | 0.86 | CNR1 (0.54) | CNR1CNR2EGFRALDH1A1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |