Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 15/20 | 0.43 |
| ▸ | MTOR | P42345 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785561 | 0.93 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL4785311 | 0.93 | PIK3CA (0.41) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL4884098 | 0.92 | PIK3CA (0.45) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL4784954 | 0.91 | PIK3CA (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4846093 | 0.89 | HRH4 (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4783926 | 0.89 | HRH4 (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4785845 | 0.89 | HRH4 (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4784093 | 0.89 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL4782301 | 0.89 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL4782401 | 0.89 | PIK3CA (0.39) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |