Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234795 | 1.00 | HTR2A (0.55) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL27774511 | 0.88 | HTR2A (0.53) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL11859185 | 0.88 | HTR2A (0.55) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL7823141 | 0.87 | HTR2A (0.50) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL3981772 | 0.86 | HTR2A (0.58) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL31273982 | 0.85 | HTR2A (0.60) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL3470487 | 0.85 | HTR2A (0.60) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL2164496 | 0.83 | HTR2A (0.57) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL2164501 | 0.83 | HTR2A (0.57) | HTR2AHTR2BHTR2CPPARGPPARA | |
| SCHEMBL7612638 | 0.83 | HTR2A (0.66) | HTR2AHTR2BHTR2CPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894195-A | Method for preparing 1-aryl-3-substituted acetone compound and intermediate | 迈克斯(如东)化工有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115894205-A | Method for preparing 1-phenyl-3- (3-trifluoromethylphenyl) -2-acetone, intermediate and application thereof | 迈克斯(如东)化工有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2008035381-A2 | PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES AS CALCIMIMETICS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |