Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | IL15 | P40933 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3040798 | 0.86 | PARP1 (0.43) | PDE4BRAB9A | |
| SCHEMBL1652642 | 0.86 | PDE4B (0.43) | PDE4B | |
| SCHEMBL1652695 | 0.80 | PDE4B (0.48) | PDE4B | |
| SCHEMBL3029577 | 0.77 | GRM4 (0.43) | PDE4B | |
| SCHEMBL4706937 | 0.77 | PDE4B (0.54) | PDE4BTP53 | |
| SCHEMBL1652702 | 0.77 | PDE4B (0.52) | PDE4BRAB9A | |
| SCHEMBL3022756 | 0.77 | PDE4B (0.47) | PDE4BRAB9ATP53 | |
| SCHEMBL3022788 | 0.76 | TP53 (0.34) | TP53CYP2C9HTT | |
| SCHEMBL3022206 | 0.75 | CSF1R (0.48) | RAB9AHTT | |
| SCHEMBL3038538 | 0.75 | PDE4B (0.45) | PDE4BRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575926-B1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | ALMIRALL LAB (ES) | 2008-03-05 | — | — | EP | disclosed |