SCHEMBL4784503

SCHEMBL4784503

CNCCCS(=O)(=O)Nc1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)ccc1C.COC(=O)c1cccc(S(=O)(=O)Nc2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)ccc2C)c1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4172347 0.91 FASN (0.57) FASN
SCHEMBL4187432 0.89 FASN (0.60) FASN
SCHEMBL4165977 0.84 FASN (0.57) FASN
SCHEMBL4177123 0.83 FASN (0.59) FASN
SCHEMBL4184508 0.83 FASN (0.58) FASN
SCHEMBL4175157 0.83 FASN (0.62) FASN
SCHEMBL4180508 0.82 FASN (0.57) FASN
SCHEMBL4165965 0.82 FASN (0.58) FASN
SCHEMBL4184087 0.82 FASN (0.57) FASN
SCHEMBL4175739 0.82 FASN (0.57) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075070-A1 SULFONAMIDE DERIVATIVES FOR THERAPEUTIC USE AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-06-26 WO disclosed