Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.48 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | CCR10 | P46092 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CALCA | P06881 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697653 | 0.89 | TACR1 (0.50) | TACR1CYP51A1CCR1 | |
| SCHEMBL4701823 | 0.79 | TACR1 (0.51) | TACR1CYP51A1CCR1 | |
| SCHEMBL4701845 | 0.76 | TACR1 (0.47) | TACR1ALDH1A1 | |
| SCHEMBL4697659 | 0.75 | TACR1 (0.51) | TACR1CYP51A1CCR1 | |
| SCHEMBL4680475 | 0.75 | TACR1 (0.52) | TACR1CYP51A1CCR1ALDH1A1 | |
| SCHEMBL4679448 | 0.74 | TACR1 (0.49) | TACR1CYP51A1CCR1 | |
| SCHEMBL4515112 | 0.74 | MC4R (0.55) | TACR1ALDH1A1 | |
| SCHEMBL4700103 | 0.74 | TACR1 (0.49) | TACR1CYP51A1CCR1 | |
| SCHEMBL4676388 | 0.74 | TACR1 (0.49) | TACR1CYP51A1CCR1 | |
| SCHEMBL4703222 | 0.72 | TACR1 (0.57) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B8 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1416933-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgem, Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003009847-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM, INC. (US) | 2003-02-06 | — | — | WO | disclosed |