Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 19/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4783748 | 1.00 | CHRM3 (0.98) | CHRM3 | |
| Iodide SCHEMBL4784581 | 0.99 | CHRM3 (0.98) | CHRM3 | |
| SCHEMBL14162469 | 0.99 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL14162443 | 0.99 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL14162201 | 0.99 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL14162144 | 0.98 | CHRM3 (1.00) | CHRM3 | |
| Iodide SCHEMBL4739820 | 0.90 | CHRM3 (0.98) | CHRM3 | |
| Iodide SCHEMBL4853054 | 0.89 | CHRM3 (0.98) | CHRM3 | |
| Iodide SCHEMBL4739995 | 0.89 | CHRM3 (0.98) | CHRM3 | |
| SCHEMBL14162118 | 0.88 | CHRM3 (1.00) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075006-A1 | PIPERLDINUM COMPOUNDS FOR TREATMENT OF OBSTRUCTIVE PULMONARY DISEASES ( COPD) | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |