Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148489 | 0.93 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148566 | 0.93 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL4742041 | 0.92 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148296 | 0.92 | HSP90AB1 (0.49) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148493 | 0.92 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL4794194 | 0.91 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148644 | 0.91 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL1147902 | 0.91 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL4787241 | 0.90 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL1147974 | 0.90 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103353-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2008-08-28 | — | — | WO | claimed |
| WO-2008103353-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008103353-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2008-08-28 | — | — | WO | disclosed |