SCHEMBL4785246

SCHEMBL4785246

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NC(C)COc1ccccc1.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NC1CCCN(C)C1.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCCN1CCC(F)(F)C1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4196008 0.83 FASN (0.57) FASN
SCHEMBL4199023 0.82 FASN (0.60) FASN
SCHEMBL4189257 0.80 FASN (0.65) FASN
SCHEMBL4782754 0.76 FASN (0.60) FASN
SCHEMBL4199015 0.75 FASN (0.62) FASN
SCHEMBL4205036 0.74 FASN (0.62) FASN
SCHEMBL4189321 0.73 FASN (0.65) FASN
SCHEMBL4206485 0.73 FASN (0.77) FASN
SCHEMBL4209364 0.73 FASN (0.77) FASN
SCHEMBL4201033 0.72 FASN (0.63) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed