Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066695 | 0.85 | CACNA1B (0.53) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3034249 | 0.83 | KMT2A (0.53) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27717488 | 0.83 | KDM4E (0.49) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6513465 | 0.82 | PTGS1 (0.60) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9620700 | 0.81 | CYSLTR2 (0.56) | TSHRALDH1A1SMN1; SMN2LMNAALOX5 | |
| SCHEMBL24080272 | 0.81 | KDM4E (0.61) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5209769 | 0.80 | KDM4E (0.44) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5209762 | 0.80 | KDM4E (0.44) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6055352 | 0.80 | TP53 (0.52) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27494801 | 0.80 | MEN1 (0.41) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |