SCHEMBL4785352

SCHEMBL4785352

CCCCNC(=O)NCCNC(=O)Nc1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)ccc1C.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCCCCCNC(=O)N1CCOCC1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4210009 0.96 FASN (0.59) FASN
SCHEMBL4191352 0.94 FASN (0.59) FASN
SCHEMBL4785343 0.91 FASN (0.47) FASN
SCHEMBL4199582 0.91 FASN (0.61) FASN
SCHEMBL4204935 0.90 FASN (0.63) FASN
SCHEMBL4203379 0.86 FASN (0.57) FASN
SCHEMBL4203648 0.85 FASN (0.58) FASN
SCHEMBL4737283 0.85 FASN (0.62) FASN
SCHEMBL4201403 0.85 FASN (0.65) FASN
SCHEMBL4209901 0.84 FASN (0.61) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed