SCHEMBL4785488

SCHEMBL4785488

N#Cc1ccc(C2CCN(C(=O)c3ccc(Cl)c(NC(=O)C4CC4)c3)CC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4736227 0.88 FASN (0.66) FASN
SCHEMBL4736925 0.85 FASN (0.58) FASN
SCHEMBL4734940 0.85 FASN (0.59) FASN
SCHEMBL4735878 0.84 FASN (0.66) FASN
SCHEMBL4786018 0.84 FASN (0.66) FASN
SCHEMBL4732690 0.84 FASN (0.60) FASN
SCHEMBL4785174 0.84 FASN (0.60) FASN
SCHEMBL4735357 0.83 FASN (0.65) FASN
SCHEMBL4171986 0.83 FASN (0.76) FASN
SCHEMBL4734570 0.83 FASN (0.55) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008059214-A1 BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-05-22 WO disclosed